Obesity reduces chances for successful IVF

At the annual meeting of the European Society of Human Reproduction and Embryology in London Spanish researchers presented their findings on the impact of female body weight on the efficiency of IVF. The scientists have studied more than 9500 cases of IVF in various clinics of the country between 2000 and 2011 years and have concluded that overweight women who pass in vitro fertilization procedure, get pregnant less often than women with normal weight. "Based on our results, we can say that the chance of having a child of obese women is decreased by about one-third",- says doctor Jose Bellver from Valencia Infertility Institute.

Researchers have compared the body mass index (BMI) of women who have been trying to conceive a child with IVF. It was found that increasing of BMI significantly decreased the frequency of embryo’s implantation in the uterus and number of pregnancies, accordingly. For example, the birth rate among slim women was 38.6%, 37.9% - among women with normal weight, 34.9% - among overweight women and 27.7% among women suffering from obesity. The frequency of the embryo’s implantation in the uterus was 40.4% among slim women - 39.9% among women with normal weight, 38.5% - among women who are overweight and 30.9% - among those who have obesity.

It is interesting that several similar researches have been already conducted this year in other European scientific centers as well: that time results showed that obesity wasn’t only significantly increasing the risk of infertility of women, but also negatively affected the health of an unborn child. Doctors explain that there is much fat, that is accumulated in a body of an obese person, so fatty acids, which are accumulated in the ovaries, have negative toxic effect on egg, which then causes reproductive disorders.

It is not the first study, that catches my eye, about role of women’s age in successful IVF procedure. It’s pretty difficult to argue with the facts and conclusions given above, even though I traditionally have doubts about the representativeness of the study, not to mention the cleanliness of the control groups. The question is - what is next? To recommend a woman who is planning to undergo IVF, to starve herself? So in fact any diet - is physically and psychologically stressful action for the body, nobody knows, if there will be more benefit or harm from the point of view of IVF. And taking into account that a woman's body will undergo gonadotropins’ therapy, seems like diet will make it only worse.

At least, if you really think about loosing weight before the IVF, make a decision only after consultation with a physician.

Moreover, there are factors that define the efficiency of IVF much stronger: such as age, condition of reproductive organs and the quality of biological material (also depends on age in many respects). So, from the point of view of the effectiveness of IVF, it is much better to pass it at the age of 33 even if a woman is overweight, than for a slim one at the age of 40. Like it or not, all other factors are secondary anyway.